Improvement of the quality of training the students of higher medical institutions is connected with the improvement of forms and methods of teaching subjects, as well as the introduction of the latest achievements of modern forms, learning the high standard and control of the level of knowledge. The materials presented in this textbook are based on the program of studying the subject “Obstetrics and Gynecology” on the position of evidence-based medicine and the transition to the Bologna process. Orders of Ministry of Public Health of Ukraine “On the Organization of Inpatient Obstetric and Neonatal Care in Ukraine”, as well as modern methods of diagnosis and treatment of gynecological patients are used in the textbook. Each unit contains test tasks and clinical cases with answers to check up the students’ knowledge. At the end of each subunit there is the list of practical skills that the students should master. For students of higher medical education institutions of the 3rd–4th levels of accreditation.