The textbook briefly reviews the basic concepts and laws of chemistry, the structure of substances, their properties, the energy and kinetics of chemical reactions. On the basis of this material, the properties of solutions and regularities of the processes occurring in them are presented. The textbook describes the properties of chemical elements, their simple and complex substances, the biological role and application in medicine. The textbook is intended for students of higher pharmaceutical education establishments and pharmaceutical faculties of higher medical education establishments.