The guide provides basic statistical data on scientific and technical potential and performance of the National Academy of Sciences of Ukraine. Representation of the place and the role of the National Academy of Sciences of Ukraine in the system of scientific organizations of the state, including in the context of the sector and in the global context is given. Statistical data mainly covers the period from 2012 and 2017. In preparing the guide benefited the State Statistics Service of Ukraine, the annual reports of the National Academy of Sciences of Ukraine and international scientometric databases and scientific publications. The publication is intended for representatives of public authorities, researchers, university students, journalists and the general public.